The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 27, 2016
Filed:
Apr. 19, 2012
Applicants:
Britta Deutel, Kundl, AT;
Thomas Lauber, Kundl, AT;
Sabine Fuertinger, Kundl, AT;
Inventors:
Assignee:
Sandoz AG, Basel, CH;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/16 (2006.01); C07K 14/705 (2006.01); C07K 14/715 (2006.01); A61K 47/12 (2006.01); A61K 47/18 (2006.01); A61K 38/17 (2006.01);
U.S. Cl.
CPC ...
C07K 14/7151 (2013.01); A61K 38/1793 (2013.01); A61K 47/12 (2013.01); A61K 47/183 (2013.01); C07K 2319/30 (2013.01);
Abstract
The present invention relates to stable pharmaceutical liquid formulations of the fusion protein TNFR:Fc comprising different buffer systems and stabilizers. In particular, it could be demonstrated that the physical stability of TNFR:Fc is significantly improved by using a citrate buffer system and lysine as stabilizer.