The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9453058 B1

PDF
Full Text
Expired
Date of Patent:
Sep. 27, 2016

Filed:

Mar. 22, 2010
Applicants:

Roland Suck, Hamburg, DE;

Helmut Fiebig, Schwarzenbek, DE;

Oliver Cromwell, Schmilau, DE;

Inventors:

Roland Suck, Hamburg, DE;

Helmut Fiebig, Schwarzenbek, DE;

Oliver Cromwell, Schmilau, DE;

Assignee:

Merck Patent GmbH, Darmstadt, DE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A01N 37/18 (2006.01); A01N 63/00 (2006.01); A61K 38/00 (2006.01); A61K 39/00 (2006.01); A61K 39/35 (2006.01); A61K 39/36 (2006.01); A61K 48/00 (2006.01); C07H 21/02 (2006.01); C07H 21/04 (2006.01); C07K 2/00 (2006.01); C07K 4/00 (2006.01); C07K 5/00 (2006.01); C07K 14/415 (2006.01);
U.S. Cl.
CPC ...
C07K 14/415 (2013.01);
Abstract

The invention relates to pharmaceutically important variants of the major allergen Phl p 1 from timothy grass, characterized in that a preparation, hitherto not possible, of monomeric molecules which are soluble and stable in physiological media can be carried out with the aid of prokaryotic expression systems and subsequent purification thereof.


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