The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 27, 2016
Filed:
Aug. 29, 2012
Gunter Fischer, Halle, DE;
Miroslav Malesevic, Halle, DE;
Frank Erdmann, Halle, DE;
Jan Kuhling, Halle, DE;
Michael Bukrinsky, Potomac, MD (US);
Stephanie Constant, Herndon, VA (US);
Gerd Ruhter, Hamburg, DE;
Peter Nussbaumer, Dortmund, DE;
Klaus Dinkel, Bochum, DE;
Gunter Fischer, Halle, DE;
Miroslav Malesevic, Halle, DE;
Frank Erdmann, Halle, DE;
Jan Kuhling, Halle, DE;
Michael Bukrinsky, Potomac, MD (US);
Stephanie Constant, Herndon, VA (US);
Gerd Ruhter, Hamburg, DE;
Peter Nussbaumer, Dortmund, DE;
Klaus Dinkel, Bochum, DE;
Max-Planck-Gesellschaft zur Forderung der Wissenschaften e.V., Munich, DE;
Lead Discovery Center GmbH, Dortmund, DE;
Abstract
The present invention relates to novel cyclosporin derivatives that do not cross the cellular membrane. The compounds according to the invention are used in medicine, more particularly in the treatment/diagnosis of acute and chronic inflammatory diseases, viral infections, cancer, degenerative muscle diseases, neurodegenerative diseases and damage that is associated with calcium homeostasis impairment. The novel cyclosporin derivatives additionally have no immunosuppressive effect.