The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 27, 2016

Filed:

Dec. 12, 2013
Applicant:

Merck Sharp & Dohme Corp., Rahway, NJ (US);

Inventors:

Songnian Lin, Holmdel, NJ (US);

Rui Zhang, Plainsboro, NJ (US);

Brian Campbell, Bensalem, PA (US);

Sunita V. Dewnani, Secaucus, NJ (US);

Jiayi Xu, Marlboro, NJ (US);

Libo Xu, Bridgewater, NJ (US);

Emma R. Parmee, Doylestown, PA (US);

Roman Kats-Kagan, New Haven, CT (US);

Assignee:

Merck Sharp & Dohme Corp., Rahway, NJ (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07F 9/6539 (2006.01); A61K 31/4439 (2006.01); C07D 401/04 (2006.01); A61K 31/444 (2006.01); C07D 471/04 (2006.01); A61K 31/437 (2006.01); C07F 9/58 (2006.01); A61K 31/675 (2006.01); A61K 31/497 (2006.01); A61K 31/427 (2006.01); C07F 9/6558 (2006.01); C07F 7/08 (2006.01); C07D 401/14 (2006.01); C07D 403/04 (2006.01); C07D 403/14 (2006.01); C07D 417/14 (2006.01);
U.S. Cl.
CPC ...
C07F 9/6539 (2013.01); A61K 31/427 (2013.01); A61K 31/437 (2013.01); A61K 31/444 (2013.01); A61K 31/4439 (2013.01); A61K 31/497 (2013.01); A61K 31/675 (2013.01); C07D 401/04 (2013.01); C07D 401/14 (2013.01); C07D 403/04 (2013.01); C07D 403/14 (2013.01); C07D 417/14 (2013.01); C07D 471/04 (2013.01); C07F 7/0812 (2013.01); C07F 9/587 (2013.01); C07F 9/65583 (2013.01);
Abstract

Novel pyridine-2-carboxamide derivatives of formula I: and pharmaceutically acceptable salts thereof are disclosed as useful for treating or preventing type 2 diabetes and similar conditions. The compounds are effective as glucokinase activating agents. Pharmaceutical compositions and methods of treatment are also included.


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