The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 27, 2016

Filed:

Mar. 14, 2014
Applicant:

Fundación Centro Nacional DE Investigaciones Oncológicas Carlos Iii, Madrid, ES;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 498/14 (2006.01); C07D 519/00 (2006.01); A61K 45/06 (2006.01); A61K 31/553 (2006.01); A61K 31/5383 (2006.01);
U.S. Cl.
CPC ...
C07D 498/14 (2013.01); A61K 31/5383 (2013.01); A61K 31/553 (2013.01); A61K 45/06 (2013.01); C07D 519/00 (2013.01);
Abstract

Provided are chemical entities selected from compounds of formula (I), wherein R, Rand m have meanings given in the description, and pharmaceutically acceptable salts, solvates and stereoisomers thereof, which are inhibitors of ATR and are potentially useful in the treatment of cancer. Further provided are pharmaceutical compositions of the chemical entities, combination products containing the chemical entities, the use of the compositions as therapeutic agents, and methods of treatment using these compositions.


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