The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 27, 2016
Filed:
Dec. 22, 2014
Dyomics Gmbh, Jena, DE;
Bernd G. Schweder, Jena, DE;
Matthias S. Wenzel, Jena, DE;
Wilhelm G. Frank, Jena, DE;
Frank G. Lehmann, Jena, DE;
Peter T. Czerney, Weimar, DE;
DYOMICS GMBH, Jena, DE;
Abstract
The invention concerns compounds based on benzoxazoles wherein selected substituents are each a reactive group A bound via a linker L and adapted to covalently bond a compound of the invention to a to-be-marked molecule K, wherein A is an amine, hydroxy or phosphoramidite function, a carboxylic acid, an alkyl or active ester derived therefrom; a carboxylic acid hydrazide; or a carboxylic acid amide where K is a covalently bound component selected from the group haptenes, proteins (antibodies), low molecular weight drug compounds, peptides, nucleotides, nucleosides, DNA oligomers, polymers, and t is from 1 to 10, and L is a linker selected from a group featuring —(CH)—, —[(CH)—O]—(CH)—, —NR10-(CH)—, —O—(CH)—, —S—(CH)—, —NR10-C(O)—(CH)—, —NR10-C(O)—O—(CH)—, —NR10-C(O)—NR11-(CH)— or —SO—NR10-(CH)—, wherein R10 and R11 are each independently hydrogen, alkyl and alkoxy-alkyl (—[(CH)—O]—CH), ω-sulfoalkyl (—(CH)—SO), m represents the numbers of 2-5, p, r and s each independently represent the number of 1-10.