The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9453003 B1

PDF
Full Text
Expired
Date of Patent:
Sep. 27, 2016

Filed:

Jun. 22, 2015
Applicant:

Jikai Biosciences, Inc., Shanghai, CN;

Inventor:

Yu Ge, Shanghai, CN;

Assignee:

Jikai Biosciences, Inc., Shanghai, CN;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/506 (2006.01); C07D 405/14 (2006.01); C07D 401/14 (2006.01); C07D 401/12 (2006.01); C07D 413/14 (2006.01); C07D 403/14 (2006.01); C07D 417/12 (2006.01); C07D 417/14 (2006.01); C07D 451/02 (2006.01); C07D 451/06 (2006.01); C07D 453/02 (2006.01); C07D 471/08 (2006.01); C07D 487/08 (2006.01); C07D 403/02 (2006.01); C07D 413/12 (2006.01);
U.S. Cl.
CPC ...
C07D 405/14 (2013.01); C07D 401/12 (2013.01); C07D 401/14 (2013.01); C07D 403/14 (2013.01); C07D 413/14 (2013.01); C07D 417/12 (2013.01); C07D 417/14 (2013.01); C07D 451/02 (2013.01); C07D 451/06 (2013.01); C07D 453/02 (2013.01); C07D 471/08 (2013.01); C07D 487/08 (2013.01); A61K 31/506 (2013.01); C07D 403/02 (2013.01); C07D 413/12 (2013.01);
Abstract

PIM kinase inhibitor compound having a structure as represented by Formula I, and isomers, diastereomers, enantiomers, tautomers, and pharmaceutically acceptable salts thereof. The compounds significantly inhibit the Pim kinase activity and are used to prepare drugs to treat PIM kinase mediated diseases, such as cancers, multi drug resistance, and inflammatory bowel disease. Also provided are methods for preparing and using the compounds represented by Formula I.


Find Patent Forward Citations

Ge, Yu. (2016). Pyrimidine derivatives as pim kinase inhibitors and preparation methods and use in medicinal manufacture thereof (U.S. Patent No. 9453003). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9453003

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