The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 27, 2016
Filed:
Jun. 19, 2013
Michael Dechantsreiter, Chestnut Hill, MA (US);
Jonathan E. Grob, Sharon, MA (US);
Aengus Macsweeney, Basel, CH;
Wolfgang Miltz, Basel, CH;
Stefan Andreas Randl, Frankfurt am Main, DE;
Richard Sedrani, Basel, CH;
Holger Sellner, Buchs, CH;
Finton Sirockin, Blotzheim, FR;
Eric Valeur, Vieux Ferrette, FR;
Michael Dechantsreiter, Chestnut Hill, MA (US);
Jonathan E. Grob, Sharon, MA (US);
Aengus Macsweeney, Basel, CH;
Wolfgang Miltz, Basel, CH;
Stefan Andreas Randl, Frankfurt am Main, DE;
Richard Sedrani, Basel, CH;
Holger Sellner, Buchs, CH;
Finton Sirockin, Blotzheim, FR;
Eric Valeur, Vieux Ferrette, FR;
NOVARTIS AG, Basel, CH;
Abstract
The present invention provides a compound of formula I a method for manufacturing the compounds of the invention, and its therapeutic uses as inhibitor of the complement alternative pathway and particularly as inhibitor of Factor B for the treatment of e.g. age-related macular degeneration and diabetic retinopathy. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.