The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 27, 2016

Filed:

Nov. 04, 2014
Applicant:

New Jersey Institute of Technology, Newark, NJ (US);

Inventors:

Kamalesh Sirkar, Bridgewater, NJ (US);

Robert Pfeffer, Scottsdale, AZ (US);

Dhananjay Singh, Kearny, NJ (US);

Dengyue Chen, Harrison, NJ (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/50 (2006.01); B82Y 30/00 (2011.01); A61K 9/51 (2006.01);
U.S. Cl.
CPC ...
B82Y 30/00 (2013.01); A61K 9/5192 (2013.01); A61K 9/50 (2013.01);
Abstract

The present disclosure relates to the field of polymer coating. The present disclosure provides improved systems and methods for continuous polymer coating of particles (e.g., nanoparticles). The present disclosure provides for a solid hollow fiber cooling crystallization (SHFCC) technique to continuously coat the nanoparticles with polymer. In certain embodiments, the present disclosure embraces continuous coating of particles from about 1 nm to about 10 microns. A polymer solution containing a suspension of submicron particles flows in the lumen of a solid polymeric hollow fiber, and controlled cooling of the polymer solution allows for polymer nucleation on the surface of the particles, and the precipitated polymer forms a thin film around the particles (the thickness of which can be varied depending on the operating conditions). The systems, methods and assemblies of the present disclosure are easily adaptable for coating nano-sized drug particles as well.


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