The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 27, 2016

Filed:

Feb. 21, 2013
Applicants:

Tin Tin Su, Boulder, CO (US);

Mara N. Gladstone, Boulder, CO (US);

Gan Zhang, Niwot, CO (US);

Tarek Sammakia, Boulder, CO (US);

Inventors:

Tin Tin Su, Boulder, CO (US);

Mara N. Gladstone, Boulder, CO (US);

Gan Zhang, Niwot, CO (US);

Tarek Sammakia, Boulder, CO (US);

Assignees:

THE REGENTS OF THE UNIVERSITY OF COLORADO, Denver, CO (US);

SUVICA, INC., Menlo Park, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 7/64 (2006.01); A61K 45/06 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
A61K 45/06 (2013.01); C07K 7/64 (2013.01); A61K 38/00 (2013.01);
Abstract

The present invention is directed at bouvardin analogs arid related compounds for the treatment of disorders including cancer. Provided herein are bouvardin analogs and related compounds, pharmaceutical compositions and kits comprising at least one bouvardin analog or related compound, and methods for treating disorders including cancer. In some aspects the compounds inhibit translation elongation at the ribosome. The compounds are used in combination with radiation therapy or with known chemotherapeutic compositions.


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