The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 27, 2016

Filed:

Jul. 03, 2013
Applicant:

Alfa Wassermann Spa, Bologna, IT;

Inventors:

Giuseppe Claudio Viscomi, Bologna, IT;

Laura Chelazzi, Bologna, IT;

Fabrizia Grepioni, Bologna, IT;

Dario Braga, Bologna, IT;

Maddalena Kindt, Bologna, IT;

Assignee:

Alfa Wassermann S.P.A, Alanno (Pescara), IT;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/437 (2006.01); A61K 9/00 (2006.01); A61K 9/16 (2006.01); A61K 9/28 (2006.01); A61K 31/198 (2006.01); A61K 31/405 (2006.01); A61K 31/4172 (2006.01); A61K 47/18 (2006.01); C07D 498/22 (2006.01); G01N 33/15 (2006.01);
U.S. Cl.
CPC ...
A61K 31/437 (2013.01); A61K 9/0095 (2013.01); A61K 9/1617 (2013.01); A61K 9/2866 (2013.01); A61K 31/198 (2013.01); A61K 31/405 (2013.01); A61K 31/4172 (2013.01); A61K 47/183 (2013.01); C07D 498/22 (2013.01); G01N 33/15 (2013.01);
Abstract

The present invention relates to rifaximin compositions comprising amino acids, characterized in that they increase rifaximin solubility in aqueous solutions and are useful in the treatment of disease wherein amino acids and rifaximin are efficacious. The present invention also relates to pharmaceutical compositions comprising rifaximin or one of the pharmaceutically acceptable salts thereof and one or more amino acid(s), wherein the molar ratio between the amino acid(s) and rifaximin is from 1:1 to 10:1, together with pharmaceutically acceptable excipients. The present invention further relates to rifaximin crystals obtained by dissolving rifaximin and amino acids in solutions formed by ethanol/water and evaporating the solution.


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