The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 27, 2016
Filed:
Dec. 27, 2013
Abbott Cardiovascular Systems Inc., Santa Clara, CA (US);
Mikael Trollsas, San Jose, CA (US);
John Stankus, Campbell, CA (US);
James Su, San Bruno, CA (US);
Syed Hossainy, hayward, CA (US);
Joshua Takeshi Smith, Campbell, CA (US);
Shadid Askar, Round Rock, TX (US);
Abbott Cardiovascular Systems Inc., Santa Clara, CA (US);
Abstract
Formulations and methods are disclosed which provide controlled, sustained release of a biologic therapeutic to a space within the body. More specifically, formulations comprising a plurality of hydrophilic polymer strands, and methods of forming and administering such formulations, are disclosed. In some embodiments, the formulations exhibit a burst release, an initial release, a triphasic release, and release over thirty to ninety days of the biologic therapeutic. In some embodiments, the formulations exhibit reversible precipitation of the biologic therapeutic into precipitates having a diameter of about 50 nm to about 10 μm.