The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 27, 2016
Filed:
Dec. 01, 2014
Applicant:
National Tsing Hua University, Hsinchu, TW;
Inventors:
Assignee:
NATIONAL TSING HUA UNIVERSITY, Hsinchu, TW;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/26 (2006.01); A61K 9/14 (2006.01); A61K 38/28 (2006.01); A61K 9/46 (2006.01); A61K 9/51 (2006.01); A61K 9/127 (2006.01); A61K 47/02 (2006.01); A61K 47/20 (2006.01);
U.S. Cl.
CPC ...
A61K 9/0007 (2013.01); A61K 9/1271 (2013.01); A61K 9/14 (2013.01); A61K 9/5123 (2013.01); A61K 9/5169 (2013.01); A61K 38/28 (2013.01); A61K 47/02 (2013.01); A61K 47/20 (2013.01); A61K 47/26 (2013.01);
Abstract
The pharmaceutical composition includes a drug layer comprising an active ingredient, a surfactant, an acidic component and an effervescent ingredient. The active ingredient comprises a nucleic acid, a peptide or a protein. The acidic component and effervescent ingredient of the drug layer are dissolved in the water to react for generating carbon dioxide and bubbles thereof. The surfactants surround the carbon dioxide gas core and form a double-layer structure having an inner layer and outer layer. The active ingredient is embedded in a gap formed between the inner layer and the outer layer of the double-layer structure.