The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 20, 2016
Filed:
Aug. 17, 2012
Applicants:
Takashi Shimada, Tsukuba, JP;
Taka-aki Sato, Tokyo, JP;
Koichi Tanaka, Kyoto, JP;
Inventors:
Assignee:
SHIMADZU CORPORATION, Kyoto, JP;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/68 (2006.01);
U.S. Cl.
CPC ...
G01N 33/6848 (2013.01); Y10T 436/145555 (2015.01); Y10T 436/147777 (2015.01); Y10T 436/173845 (2015.01); Y10T 436/19 (2015.01); Y10T 436/200833 (2015.01); Y10T 436/24 (2015.01);
Abstract
A thiol probe for a protein, which promotes ionization in proteomic analysis using mass spectrometry and can be used even for a protein that has a high degree of hydrophobicity and quickly turns over, and is represented by the following formula (I): In formula (I), Rrepresents a linker group, and Rrepresents a substituted ammonium group or a substituted amino group. A mass spectrometry method for a protein, includes the steps of obtaining a modified protein by reacting the thiol probe with a protein to be subjected to mass spectrometry and subjecting the modified protein to mass spectrometry.