The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 20, 2016

Filed:

Mar. 08, 2012
Applicants:

Younghoon Kim, Champaign, IL (US);

Sung Hoon Kim, Champaign, IL (US);

Melikhan Tanyeri, Champaign, IL (US);

John A. Katzenellenbogen, Urbana, IL (US);

Charles M. Schroeder, Iii, Champaign, IL (US);

Inventors:

Younghoon Kim, Champaign, IL (US);

Sung Hoon Kim, Champaign, IL (US);

Melikhan Tanyeri, Champaign, IL (US);

John A. Katzenellenbogen, Urbana, IL (US);

Charles M. Schroeder, III, Champaign, IL (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 33/58 (2006.01); G01N 21/64 (2006.01); C08G 73/14 (2006.01); C08G 83/00 (2006.01); C08G 73/02 (2006.01);
U.S. Cl.
CPC ...
G01N 21/6428 (2013.01); C08G 73/14 (2013.01); G01N 21/6456 (2013.01); G01N 33/582 (2013.01); G01N 33/585 (2013.01); C08G 73/028 (2013.01); C08G 83/003 (2013.01); G01N 2021/6441 (2013.01); Y10S 977/707 (2013.01);
Abstract

The invention provides dendrimers, conjugates thereof, and methods of using dendrimer conjugates. In one embodiment, the invention provides novel polymeric dendrimers as a new class of fluorescent labels. The labels can include multiple fluorescent dye molecules conjugated to a single polymeric backbone or core, such as a dendrimer. The dendrimers can have regular or irregular branched polymeric network structures that allow for the chemical attachment of multiple dye molecules, multiple color dyes, and/or multiple functional groups, in a combinatorial fashion. The fluorescent dendritic nanoprobes (FDNs) thus provide a new class of fluorescent reporters for fluorescence microscopy and imaging.


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