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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9447439 B1

PDFFull Text
Date of Patent:
Sep. 20, 2016

Filed:

Aug. 25, 2014

Microorganism producing 4-hydroxybutyrate and a method for producing 4-hydroxybutyrate in anaerobic condition using the same

Applicant:

Samsung Electronics Co., Ltd., Suwon-si, Gyeonggi-do, KR;

Inventors:

Youngmin Lee, Suwon-si, KR;

Wooyong Lee, Hwaseong-si, KR;

Jinwoo Kim, Seoul, KR;

Jaechan Park, Yongin-si, KR;

Jinhwan Park, Suwon-si, KR;

Hwayoung Cho, Hwaseong-si, KR;

Assignee:

SAMSUNG ELECTRONICS CO., LTD., Suwon-Si, KR;

Attorney:

Leydig, Voit & Mayer, Ltd.

Primary Examiner:

Suzanne M Noakes

Int. Cl.
CPC ...
C12P 7/42 (2006.01); C12N 9/00 (2006.01); C12P 7/46 (2006.01); C12N 9/02 (2006.01); C12P 17/04 (2006.01);
U.S. Cl.
CPC ...
C12P 7/42 (2013.01); C12N 9/0008 (2013.01); C12N 9/93 (2013.01); C12P 7/46 (2013.01); C12P 17/04 (2013.01); C12Y 101/01027 (2013.01); C12Y 103/05 (2013.01); C12Y 401/01 (2013.01); C12Y 101/01061 (2013.01); C12Y 102/01002 (2013.01); C12Y 102/01024 (2013.01); C12Y 102/07003 (2013.01); C12Y 108/01004 (2013.01); C12Y 203/01012 (2013.01); C12Y 208/03 (2013.01); C12Y 604/01001 (2013.01); Y02P 20/52 (2015.11);
Abstract

A genetically modified microorganism comprising a polynucleotide encoding α-ketoglutarate synthase or a mutant thereof, and a polynucleotide encoding pyruvate carboxylase or a mutant thereof; wherein the genetically modified microorganism has decreased malate quinone oxidoreductase activity and/or decreased phosphoenolpyruvate carboxykinase activity compared to an unmodified microorganism of the same type, and wherein the genetically modified microorganism produces 4-hydroxybutyrate.

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