The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 20, 2016
Filed:
Apr. 15, 2011
Applicants:
Keiichi Fukuda, Tokyo, JP;
Shinsuke Yuasa, Tokyo, JP;
Tomohisa Seki, Tokyo, JP;
Mamoru Hasegawa, Tsukuba, JP;
Inventors:
Keiichi Fukuda, Tokyo, JP;
Shinsuke Yuasa, Tokyo, JP;
Tomohisa Seki, Tokyo, JP;
Mamoru Hasegawa, Tsukuba, JP;
Assignees:
Keio University, Tokyo, JP;
DNAVEC Corporation, Ibaraki, JP;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/86 (2006.01); C12N 5/074 (2010.01);
U.S. Cl.
CPC ...
C12N 15/86 (2013.01); C12N 5/0696 (2013.01); C12N 2501/2302 (2013.01); C12N 2501/515 (2013.01); C12N 2501/602 (2013.01); C12N 2501/603 (2013.01); C12N 2501/604 (2013.01); C12N 2501/606 (2013.01); C12N 2502/13 (2013.01); C12N 2506/11 (2013.01); C12N 2510/00 (2013.01);
Abstract
An object of the present invention is to provide methods for producing iPS cells with low invasivity and high efficiency. The iPS cells can be produced with high efficiency using a method comprising the steps of culturing mononuclear cells derived from peripheral blood for 3 to 14 days in the presence of anti-CD3 antibody, and subjecting the cultured mononuclear cells to dedifferentiation.