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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9447410 B1

PDFFull Text
Date of Patent:
Sep. 20, 2016

Filed:

Apr. 10, 2014

T cell receptor display

Applicants:

Adaptimmune Limited, Oxford, GB;

Immunocore Limited, Abingdon, Oxfordshire, GB;

Inventors:

Bent Karsten Jakobsen, Oxfordshire, GB;

Peter Eamon Molloy, Oxfordshire, GB;

Yi Li, Oxfordshire, GB;

Jonathan Michael Boulter, Blackwood, GB;

Assignees:

ADAPTIMMUNE LIMITED, Abingdon Oxfordshire, GB;

IMMUNOCORE LIMITED, Abingdon Oxfordshire, GB;

Attorneys:

Vedder Price P.C.

Thomas J. Kowalski

Deborah L. Lu

Primary Examiner:

Christian Boesen

Int. Cl.
CPC ...
C40B 40/10 (2006.01); C12N 15/10 (2006.01); C07K 14/725 (2006.01); C12N 7/00 (2006.01); C40B 40/02 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C12N 15/1037 (2013.01); C07K 14/7051 (2013.01); C12N 7/00 (2013.01); C12N 15/1041 (2013.01); C12N 15/1058 (2013.01); C40B 40/02 (2013.01); A61K 38/00 (2013.01); C12N 2795/18121 (2013.01); C12N 2795/18143 (2013.01); C40B 40/10 (2013.01);
Abstract

A proteinaceous particle, for example a bacteriophage, ribosome or cell, displaying on its surface a T-cell receptor (TCR). The displayed TCR is preferably a heterodimer having a non-native disulfide bond between constant domain residues. Such display particles may be used for the creation of diverse TCR libraries for the identification of high affinity TCRs. Several high affinities are disclosed.

Find Patent Forward Citations

Jakobsen, Bent. (2016). T cell receptor display (U.S. Patent No. 9447410). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9447410

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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