The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 20, 2016

Filed:

Apr. 15, 2015
Applicant:

The Regents of the University of Colorado, Denver, CO (US);

Inventors:

Jan P Kraus, Littleton, CO (US);

Tomas Majtan, Aurora, CO (US);

Erez Bublil, Ets Efraim, IL;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/54 (2006.01); A61K 38/00 (2006.01); C12N 9/96 (2006.01); C12N 9/88 (2006.01); C07H 21/04 (2006.01); C07K 1/00 (2006.01); A61K 45/06 (2006.01); A61K 31/198 (2006.01); A61K 31/205 (2006.01); A61K 31/385 (2006.01); A61K 9/00 (2006.01); A61K 47/48 (2006.01); A61K 38/51 (2006.01);
U.S. Cl.
CPC ...
C12N 9/96 (2013.01); A61K 9/0019 (2013.01); A61K 31/198 (2013.01); A61K 31/205 (2013.01); A61K 31/385 (2013.01); A61K 45/06 (2013.01); A61K 47/48215 (2013.01); C12N 9/88 (2013.01); A61K 38/51 (2013.01); C12Y 402/01022 (2013.01);
Abstract

The invention provides reagents and methods for enzyme replacement therapy using chemically modified species of human cystathionine β-synthase (CBS) to treat homocystinuria and other related diseases and disorders.


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