The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 20, 2016

Filed:

Oct. 03, 2013
Applicant:

Merck Sharp & Dohme Corp., Rahway, NJ (US);

Inventors:

Tessie B. McNeely, Gwynedd Valley, PA (US);

Leslie Cope, Hatfield, PA (US);

Sharon Smith, Downington, PA (US);

Amita Joshi, Lansdale, PA (US);

Irene Pak, New Brunswick, NJ (US);

Arthur Fridman, East Norriton, PA (US);

Assignee:

Merck Sharp & Dohme Corp., Rahway, NJ (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 14/31 (2006.01); A61K 39/085 (2006.01); C12N 9/88 (2006.01); A61K 38/00 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C12N 9/88 (2013.01); A61K 39/085 (2013.01); C07K 14/31 (2013.01); A61K 38/00 (2013.01); A61K 2039/55505 (2013.01); A61K 2039/6037 (2013.01);
Abstract

The present invention relates to peptides of the enolase protein fromas well as nucleic acid and nucleic acid sequence homologs encoding the peptides. The present invention also relates to a composition, particularly avaccine, comprising one or more of the enolase peptides described herein or a fragment, derivative or variant thereof capable of generating an immune response that induces a protective antibody response or opsonophagocytic activity of human neutrophils for. The present invention also encompasses methods of treating and/or reducing the likelihood of ainfection by administering a composition of the invention.


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