The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 20, 2016
Filed:
May. 11, 2012
Applicants:
Hiroshi Takayanagi, Tokyo, JP;
Takako Negishi, Tokyo, JP;
Inventors:
Hiroshi Takayanagi, Tokyo, JP;
Takako Negishi, Tokyo, JP;
Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); A61K 39/395 (2006.01); C07K 16/28 (2006.01); G01N 33/50 (2006.01); G01N 33/53 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2896 (2013.01); C07K 16/28 (2013.01); C07K 16/2803 (2013.01); G01N 33/5008 (2013.01); G01N 33/53 (2013.01); A61K 38/00 (2013.01); A61K 2039/505 (2013.01); G01N 2500/00 (2013.01); G01N 2800/10 (2013.01);
Abstract
The purpose of the present invention is to provide an osteogenesis promoter for directly promoting osteogenesis by osteoblasts, and an agent for preventing and treating bone disease. The present invention is characterized in that a binding inhibitor substance of semaphorin 4D and plexin B1 is used. For the binding inhibitor substance, suitable examples include anti-semaphorin 4D antibody, anti-plexin B1 antibody, and protein comprising the extracellular domain of plexin B1.