The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 20, 2016

Filed:

Jun. 28, 2012
Applicants:

Christian Rohlff, Abingdon, GB;

Alasdair Stamps, Abingdon, GB;

Inventors:

Christian Rohlff, Abingdon, GB;

Alasdair Stamps, Abingdon, GB;

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); C07K 16/18 (2006.01); A61K 39/00 (2006.01); C07K 16/00 (2006.01); C07K 16/28 (2006.01); C07K 16/30 (2006.01); C12Q 1/68 (2006.01); G01N 33/574 (2006.01); C07K 14/435 (2006.01); G01N 33/566 (2006.01);
U.S. Cl.
CPC ...
C07K 16/18 (2013.01); A61K 39/0011 (2013.01); C07K 14/435 (2013.01); C07K 16/005 (2013.01); C07K 16/2896 (2013.01); C07K 16/30 (2013.01); C12Q 1/6886 (2013.01); G01N 33/566 (2013.01); G01N 33/57426 (2013.01); C07K 2317/55 (2013.01); C07K 2317/732 (2013.01); C07K 2317/77 (2013.01); C12Q 2600/158 (2013.01); G01N 2500/04 (2013.01);
Abstract

The present invention provides methods and compositions for treatment, screening, diagnosis and prognosis of acute myeloid leukemia (AML), B-cell chronic lymphocytic leukemia, breast cancer, colorectal cancer, kidney cancer, head and neck cancer, lung cancer, ovarian cancer or pancreatic cancer, for monitoring the effectiveness of acute myeloid leukemia (AML), B-cell chronic lymphocytic leukemia, breast cancer, colorectal cancer, kidney cancer, head and neck cancer, lung cancer, ovarian cancer or pancreatic cancer treatment, and for drug development. The present invention also provides methods and compositions for depletion of immune cells to treat inflammatory diseases.


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