The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 20, 2016
Filed:
Oct. 08, 2015
Applicant:
Moderna Therapeutics, Inc., Cambridge, MA (US);
Inventors:
Jason P. Schrum, Philadelphia, PA (US);
Stephane Bancel, Cambridge, MA (US);
Noubar B. Afeyan, Cambridge, MA (US);
Kenechi Ejebe, New York, NY (US);
Assignee:
Moderna Therapeutics, Inc., Cambridge, MA (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/04 (2006.01); A61K 31/70 (2006.01); C07K 14/685 (2006.01); A61K 31/395 (2006.01); A61K 31/7088 (2006.01); A61K 31/7115 (2006.01); A61K 38/13 (2006.01); A61K 38/19 (2006.01); A61K 38/28 (2006.01); C07K 14/62 (2006.01); A01K 67/00 (2006.01); A61K 38/00 (2006.01); A61K 48/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/685 (2013.01); A61K 31/395 (2013.01); A61K 31/7088 (2013.01); A61K 31/7115 (2013.01); A61K 38/13 (2013.01); A61K 38/193 (2013.01); A61K 38/28 (2013.01); C07K 14/62 (2013.01); A61K 38/00 (2013.01); A61K 48/00 (2013.01);
Abstract
Provided are compositions and methods for delivering biological moieties such as modified nucleic acids into cells to modulate protein expression. Such compositions and methods include the use of modified messenger RNAs, and are useful to treat or prevent diseases, disorders or conditions, or to improve a subject's heath or wellbeing.