The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 20, 2016
Filed:
Jan. 18, 2013
Applicant:
University of Miami, Miami, FL (US);
Inventors:
Izidore Lossos, Miami, FL (US);
Shruti Bhatt, Miami, FL (US);
Joseph Rosenblatt, Hollywood, FL (US);
Seung-Uon Shin, Miami, FL (US);
Assignee:
UNIVERSITY OF MIAMI, Miami, FL (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01); C07K 16/00 (2006.01); C07K 14/55 (2006.01); C07K 14/54 (2006.01); C07K 16/28 (2006.01); A61K 38/20 (2006.01); A61K 39/395 (2006.01); A61K 45/06 (2006.01); A61K 51/00 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/55 (2013.01); A61K 38/2013 (2013.01); A61K 39/39558 (2013.01); A61K 45/06 (2013.01); A61K 51/00 (2013.01); C07K 14/54 (2013.01); C07K 16/2887 (2013.01); A61K 38/00 (2013.01); A61K 2039/505 (2013.01); C07K 2317/54 (2013.01); C07K 2317/55 (2013.01); C07K 2317/73 (2013.01); C07K 2317/732 (2013.01); C07K 2317/76 (2013.01); C07K 2319/00 (2013.01); C07K 2319/33 (2013.01);
Abstract
The present invention is directed to fusion proteins having an IL-21 cytokine portion and an anti-CD20 antibody portion, and methods of using such fusion proteins. The invention also provides pharmaceutical compositions and kits utilizing the IL-21-anti-CD20 fusion proteins. In particular, the methods, kits and compositions of the invention are useful in the treatment of cancer and autoimmune diseases.