The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 20, 2016
Filed:
Sep. 18, 2013
University of Rochester, Rochester, NY (US);
University of Guelph, Guelph, CA;
The Los Angeles Biomedical Research Institute AT Harbor-ucla Medical Center, Torrance, CA (US);
Robert H. Notter, Pittsford, NY (US);
Zhengdong Wang, Rochester, NY (US);
Adrian L. Schwan, Guelph, CA;
Zhongyi Wang, Guelph, CA;
Jason A. Davy, Guelph, CA;
Alan J Waring, Irvine, CA (US);
Frans Walther, Renondo Beach, CA (US);
Larry M. Gordon, Torrance, CA (US);
University of Rochester, Rochester, NY (US);
The Los Angeles Biomedical Research Institute of Harbor-UCLA Medical Center, Torrance, CA (US);
University of Guelph, Guelph, Ontario, CA;
Abstract
The present invention relates to synthetic lung surfactant compositions that contain one or more of phospholipase-resistant phospho-glycerol derivatives, phospholipase-resistant phospho-choline derivatives, and surface active proteins or peptides, more preferably a combination of at least two or all three of these materials. Novel phospholipase-resistant phospho-glycerol derivatives, phospholipase-resistant phospho-choline derivatives, and surface active peptides are also disclosed herein. Uses of the surfactant compositions of the present invention to treat endogenous surfactant dysfunctional or deficient lung tissue, to prepare synthetic peptides for use in the surfactant compositions, and to deliver therapeutic agents are also disclosed.