The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 20, 2016
Filed:
Mar. 19, 2015
Applicant:
Astrazeneca Ab, Sodertalje, SE;
Inventors:
Bruce Edward Tomczuk, Collegeville, PA (US);
Gary Lee Olson, Mountainside, NJ (US);
Richard Scott Pottorf, Belle Mead, NJ (US);
Lijuan Jane Wang, Wildwood, MO (US);
Bhaskara Rao Nallaganchu, Hillsborough, NJ (US);
Yanqun Zhang, East Brunswick, NJ (US);
Assignee:
AstraZeneca AB, Södertälje, SE;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07F 5/02 (2006.01); A61K 31/69 (2006.01); A61K 51/04 (2006.01); C07J 43/00 (2006.01); A61K 49/00 (2006.01);
U.S. Cl.
CPC ...
C07F 5/025 (2013.01); A61K 31/69 (2013.01); C07F 5/02 (2013.01); C07J 43/003 (2013.01); A61K 49/0004 (2013.01); A61K 51/044 (2013.01);
Abstract
The present invention includes arginase enzyme inhibitors, compositions comprising these arginase inhibitors, and methods of treating or diagnosing conditions characterized either by abnormally high arginase activity or abnormally low nitric oxide levels in a mammal, comprising administering compositions of the invention to the mammal.