The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 20, 2016
Filed:
Sep. 27, 2012
Roche Carolina Inc., Florence, SC (US);
Stephan Bachmann, Allschwil, CH;
Daniel Bailey, Buffalo, NY (US);
Jodie Brice, Florence, SC (US);
Miall Cedilote, Florence, SC (US);
Zhiming Dong, Florence, SC (US);
Stefan Hildbrand, Gelterkinden, CH;
Doreen Miller, Greensboro, NC (US);
Paul Spurr, Riehen, CH;
Amit Srivastava, Aiken, SC (US);
Juergen Wichmann, Steinen, DE;
Thomas Woltering, Freiburg, DE;
Jason Yang, Pleasanton, CA (US);
Pingsheng Zhang, Florence, SC (US);
Hoffmann-La Roche Inc., Little Falls, NJ (US);
Abstract
The present invention provides methods for preparing 5-[2-[7-(trifluoromethyl)-5-[4-(trifluoromethyl)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]ethynyl]-2-pyridinamine (compound A), which is useful for the treatment of depression and other CNS disorders. The present methods are useful for preparing compound A on large scale in manufacturing facilities.