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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9447079 B1

PDFFull Text
Date of Patent:
Sep. 20, 2016

Filed:

Mar. 14, 2014

Prmt1 inhibitors and uses thereof

Applicant:

Epizyme, Inc., Cambridge, MA (US);

Inventors:

Lorna Helen Mitchell, Cambridge, MA (US);

Gideon Shapiro, Gainesville, FL (US);

Richard Chesworth, Concord, MA (US);

Paula Ann Boriack-Sjodin, Lexington, MA (US);

Oscar Miguel Moradei, Burlington, MA (US);

Kevin Wayne Kuntz, Woburn, MA (US);

Assignee:

Epizyme, Inc., Cambridge, MA (US);

Attorney:

Wolf, Greenfield & Sacks, P.C.

Primary Examiner:

Shawquia Jackson

Int. Cl.
CPC ...
C07D 401/12 (2006.01); C07D 405/12 (2006.01); C07D 231/12 (2006.01); A61K 31/415 (2006.01); A61K 31/455 (2006.01);
U.S. Cl.
CPC ...
C07D 405/12 (2013.01); A61K 31/415 (2013.01); A61K 31/455 (2013.01); C07D 231/12 (2013.01); C07D 401/12 (2013.01);
Abstract

Described herein are compounds of Formula (I-a) and (I-b), pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof. Compounds of the present invention are useful for inhibiting PRMT1 activity. Methods of using the compounds for treating PRMT1-mediated disorders are also described.

Find Patent Forward Citations

Mitchell, Lorna. (2016). Prmt1 inhibitors and uses thereof (U.S. Patent No. 9447079). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9447079

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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