The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 20, 2016
Filed:
Jan. 18, 2013
Applicant:
Acucela Inc., Seattle, WA (US);
Inventors:
Vladimir A. Kuksa, Bothell, WA (US);
Mark W. Orme, Seattle, WA (US);
Feng Hong, Bellevue, WA (US);
Ryo Kubota, Seattle, WA (US);
Assignee:
ACUCELA INC., Seattle, WA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 213/36 (2006.01); C07D 213/42 (2006.01); C07D 405/12 (2006.01); C07D 207/36 (2006.01); C07D 213/38 (2006.01); C07D 213/64 (2006.01); C07D 213/71 (2006.01); C07D 239/34 (2006.01); C07D 249/04 (2006.01); C07D 277/28 (2006.01); C07D 307/52 (2006.01); C07D 307/58 (2006.01); C07D 307/66 (2006.01); C07D 333/20 (2006.01); C07D 333/32 (2006.01); C07D 333/36 (2006.01); C07D 401/12 (2006.01); C07D 213/74 (2006.01); C07D 333/16 (2006.01); C07D 333/34 (2006.01); C07D 213/30 (2006.01); C07D 213/65 (2006.01); C07D 213/68 (2006.01); C07D 213/70 (2006.01); C07D 307/42 (2006.01);
U.S. Cl.
CPC ...
C07D 405/12 (2013.01); C07D 207/36 (2013.01); C07D 213/30 (2013.01); C07D 213/38 (2013.01); C07D 213/64 (2013.01); C07D 213/65 (2013.01); C07D 213/68 (2013.01); C07D 213/70 (2013.01); C07D 213/71 (2013.01); C07D 213/74 (2013.01); C07D 239/34 (2013.01); C07D 249/04 (2013.01); C07D 277/28 (2013.01); C07D 307/42 (2013.01); C07D 307/52 (2013.01); C07D 307/58 (2013.01); C07D 307/66 (2013.01); C07D 333/16 (2013.01); C07D 333/20 (2013.01); C07D 333/32 (2013.01); C07D 333/34 (2013.01); C07D 333/36 (2013.01); C07D 401/12 (2013.01);
Abstract
The present invention relates generally to compositions and methods for treating neurodegenerative diseases and disorders, particularly ophthalmic diseases and disorders. Provided herein are substituted heterocyclic amine derivative compound and pharmaceutical compositions comprising these compounds. The subject compositions are useful for treating and preventing ophthalmic diseases and disorders, including age-related macular degeneration (AMD) and Stargardt's Disease.