The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 20, 2016

Filed:

Nov. 05, 2013
Applicant:

Lg Life Sciences Ltd., Seoul, KR;

Inventors:

Young Kwan Kim, Daejeon, KR;

Myoung Yeol Kim, Daejeon, KR;

Sang Yun Park, Daejeon, KR;

Ok Ku Park, Daejeon, KR;

Vasily Artemov, Daejeon, KR;

Sang Dae Lee, Daejeon, KR;

Hyun Woo Joo, Daejeon, KR;

Eun Sil Choi, Daejeon, KR;

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 213/70 (2006.01); A61K 31/44 (2006.01); C07D 213/80 (2006.01); C07D 241/18 (2006.01);
U.S. Cl.
CPC ...
C07D 213/70 (2013.01); A61K 31/44 (2013.01); C07D 213/80 (2013.01); C07D 241/18 (2013.01);
Abstract

The present invention relates to thioaryl derivatives of Formula 1 as defined in the specification, a method for preparing the same, a pharmaceutical composition comprising the same and use thereof. The thioaryl derivatives of Formula 1 according to the present invention promote GLP-1 formation in the gastrointestinal tract and improve insulin resistance in macrophages, pancreas cells, etc. due to anti-inflammatory action, and can accordingly be effectively used for preventing or treating diabetes, complications of diabetes, inflammation, obesity, non-alcoholic fatty liver, steatohepatitis or osteoporosis.


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