The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9447016 B1

PDF
Full Text
Expired
Date of Patent:
Sep. 20, 2016

Filed:

Feb. 28, 2013
Applicant:

Prometic Biosciences Inc., Laval, CA;

Inventors:

Zacharie Boulos, Laval, CA;

Jean-Simon Duceppe, St. Jérôme, CA;

Christopher Penney, Pierrefonds, CA;

Assignee:

Prometic Pharma SMT Limited, Comberton, Cambridge, GB;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A23D 9/00 (2006.01); C07C 67/08 (2006.01); A61K 47/14 (2006.01); C11C 3/02 (2006.01); A61K 31/225 (2006.01); A61K 31/23 (2006.01); A61K 31/337 (2006.01); A61K 31/513 (2006.01); A61K 31/675 (2006.01); A61K 31/704 (2006.01); A61K 31/7068 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
C07C 67/08 (2013.01); A61K 31/225 (2013.01); A61K 31/23 (2013.01); A61K 31/337 (2013.01); A61K 31/513 (2013.01); A61K 31/675 (2013.01); A61K 31/704 (2013.01); A61K 31/7068 (2013.01); A61K 45/06 (2013.01); A61K 47/14 (2013.01); C11C 3/02 (2013.01); C11C 3/025 (2013.01);
Abstract

A method is disclosed for the preparation of glycerol esters (triglycerides) of medium-chain length monocarboxylic fatty acids which consists of the reaction of the precursor free fatty acid and glycerol in the presence of a catalyst under partial vacuum. The process preferably uses a metal catalyst such as an oxide or a chloride of tungsten, molybdenum, calcium, zinc, chromium or magnesium. The method of the invention allows the preparation in high yield and high purity (>99.5%) of the final triglyceride. The present method allows the formation of triglycerides without solvent. Are also contemplated, the triglyceride obtained by the method, and the pharmaceutical composition containing the triglyceride as an excipient or as an active ingredient.


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