The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 20, 2016
Filed:
Dec. 23, 2008
Benjamin Daelken, Frankfurt am Main, DE;
Christoph Uherek, Seligenstadt, DE;
Kenneth Anderson, Wellesley, MA (US);
Teru Hideshima, Brookline, MA (US);
Christoph Bruecher, Eschborn, DE;
Frank Osterroth, Dietzenbach, DE;
Silke Aigner, Frankenthal, DE;
Matthias Germer, Langen, DE;
Benjamin Daelken, Frankfurt am Main, DE;
Christoph Uherek, Seligenstadt, DE;
Kenneth Anderson, Wellesley, MA (US);
Teru Hideshima, Brookline, MA (US);
Christoph Bruecher, Eschborn, DE;
Frank Osterroth, Dietzenbach, DE;
Silke Aigner, Frankenthal, DE;
Matthias Germer, Langen, DE;
BIOTEST AG, Dreieich, DE;
IMMUNOGEN INC., Waltham, MA (US);
Dana-Farber Cancer Institute, Boston, MA (US);
Abstract
Disclosed are immunoconjugates having specificity for CD138 that diminish adhesion of CD138 expressing tumor cells to stroma cells and methods of using the same. This diminished adhesion renders the tumor cells not only susceptible to the immunoconjugate, but also to other agents, in particular cytotoxic agents.