The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 20, 2016

Filed:

Oct. 24, 2007
Applicants:

David W. Krempin, Temecula, CA (US);

Laurie Krempin, Temecula, CA (US);

Mary A. Murray, Irvine, CA (US);

Yumei Lin, Long Beach, CA (US);

Kevin W. Gellenbeck, Poway, CA (US);

Silvia R. Da Costa, Redondo Beach, CA (US);

Leon M. Wilkins, North Andover, MA (US);

Haeri Roh-schmidt, Stockton, CA (US);

Jatinder Rana, Grand Rapids, MI (US);

John F. Rebhun, Greenville, MI (US);

David J. Fast, Grand Rapids, MI (US);

Inventors:

David W. Krempin, Temecula, CA (US);

Mary A. Murray, Irvine, CA (US);

Yumei Lin, Long Beach, CA (US);

Kevin W. Gellenbeck, Poway, CA (US);

Silvia R. da Costa, Redondo Beach, CA (US);

Leon M. Wilkins, North Andover, MA (US);

Haeri Roh-Schmidt, Stockton, CA (US);

Jatinder Rana, Grand Rapids, MI (US);

John F. Rebhun, Greenville, MI (US);

David J. Fast, Grand Rapids, MI (US);

Assignee:

Other;

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 36/87 (2006.01); A61K 36/489 (2006.01); A61K 31/352 (2006.01); A61K 36/185 (2006.01); A61K 36/258 (2006.01); A61K 36/484 (2006.01); A61K 36/804 (2006.01);
U.S. Cl.
CPC ...
A61K 36/489 (2013.01); A61K 31/352 (2013.01); A61K 36/185 (2013.01); A61K 36/258 (2013.01); A61K 36/484 (2013.01); A61K 36/804 (2013.01); A61K 36/87 (2013.01);
Abstract

Disclosed herein are dietary supplement compositions and methods for increasing or stimulating bone growth, decreasing or preventing bone resorption, increasing bone strength, improving bone structure, and improving bone architecture comprising a first composition comprising a combination of at least two of: quercetin,sp.,sp. root, Siberian ginseng,, licorice, and ipriflavone, wherein the combination of the first composition increases bone morphogenic protein-2 gene, promoter or protein expression; and a second composition comprising an extract of pomegranate in combination with at least one of Siberian ginseng,, green tea,sp., grape seed, Dong Quai, and ipriflavone, wherein the combination of the second composition inhibits the expression of RANK-L.


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