The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 20, 2016

Filed:

Nov. 27, 2013
Applicant:

Toray Industries, Inc., Tokyo, JP;

Inventors:

Tatsuya Kishikawa, Otsu, JP;

Masahiro Osabe, Otsu, JP;

Yoshiyuki Ueno, Otsu, JP;

Masaaki Shimagaki, Urayasu, JP;

Shigenori Tanaka, Ibaraki, JP;

Tomoya Hayashi, Ibaraki, JP;

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 35/14 (2015.01); C12N 5/00 (2006.01); C12N 5/02 (2006.01); A61K 35/19 (2015.01); B01D 71/68 (2006.01); B01D 71/44 (2006.01); A61M 1/34 (2006.01); B01D 63/02 (2006.01); B01D 61/14 (2006.01);
U.S. Cl.
CPC ...
A61K 35/19 (2013.01); A61M 1/34 (2013.01); B01D 61/147 (2013.01); B01D 63/02 (2013.01); B01D 71/44 (2013.01); B01D 71/68 (2013.01); B01D 2315/10 (2013.01); B01D 2325/36 (2013.01);
Abstract

A method of producing a platelet solution replaced with an artificial preservation solution includes a filtering step of carrying out cross-flow filtration of a platelet solution under the conditions of Formula (1) at an inlet wall shear rate of 25 to 1500 susing a separation membrane whose surface which contacts with the platelet solution has an average pore size of not less than 0.1 μm and less than 2.0 μm, thereby obtaining a concentrated platelet solution; and a mixing step of mixing the concentrated platelet solution with an artificial preservation solution to obtain the platelet solution replaced with an artificial preservation solution:1.0×10<()/(γ×μ)≦2.5×10(platelets/(hr·m·Pa))  (1)


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