The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 20, 2016
Filed:
Jul. 09, 2015
Dogwood Pharmaceuticals, Inc., Wilmington, DE (US);
Wieslaw M. Cholody, Frederick, MD (US);
Yi Zang, Princeton Junction, NJ (US);
Karina Zuck, Derwood, MD (US);
Jeffrey W. H. Watthey, Frederick, MD (US);
Zoe Ohler, Ijamsville, MD (US);
Jeffrey Strovel, Laurel, MD (US);
Gene Ohler, Ijamsville, MD (US);
Sheela Chellappan, Germantown, MD (US);
Janak Padia, Germantown, MD (US);
Dogwood Pharmaceuticals, Inc., Wilmington, DE (US);
Abstract
Chemical agents, such as disulfonamide derivatives of fluorene, anthracene, xanthene, dibenzosuberone and acridine, and similar heterocyclic ring structures, including salts thereof, that act as anti-cancer and anti-tumor agents, especially where such agents modulate the activity of the Wnt/β-catenin signaling pathway, and serve to reduce β-catenin levels present in cells, such as cancer cells, or where the agents modulate levels of gene expression in cellular systems, including cancer cells, are disclosed, along with methods for preparing such agents, as well as pharmaceutical compositions containing such agents as active ingredients and methods of using these as therapeutic agents.