The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 20, 2016
Filed:
Aug. 16, 2013
Applicant:
Nioxx Llc, Dickinson, TX (US);
Inventors:
Cheng-Shing Chen, Taichung, TW;
Ferid Murad, McLean, VA (US);
Kenneth A Smith, Houston, TX (US);
William A Seitz, Dickinson, TX (US);
William J Merrell, Galveston, TX (US);
Alexandru T Balaban, Galveston, TX (US);
Assignee:
NIOXX LLC, Dickinson, TX (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/14 (2006.01); A01N 59/14 (2006.01); A61K 9/70 (2006.01); A61K 33/00 (2006.01); A61K 31/341 (2006.01); A61K 33/22 (2006.01); A61K 31/194 (2006.01); A61K 47/36 (2006.01); A61K 9/06 (2006.01); A61K 9/50 (2006.01); A61K 31/19 (2006.01); A61K 31/375 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
A61K 9/14 (2013.01); A01N 59/14 (2013.01); A61K 9/06 (2013.01); A61K 9/5047 (2013.01); A61K 9/5052 (2013.01); A61K 9/70 (2013.01); A61K 31/19 (2013.01); A61K 31/194 (2013.01); A61K 31/341 (2013.01); A61K 31/375 (2013.01); A61K 33/00 (2013.01); A61K 33/22 (2013.01); A61K 47/36 (2013.01); A61K 45/06 (2013.01);
Abstract
Methods and compositions are provided for generating and applying long-lasting therapeutic nitric oxide (NO) gas from the reaction of a least one microencapsulated nitrite salt and an activating volume of an aqueous acidified gel that has sufficient acidity to convert the nitrite salt to a nitric oxide (NO) and further provides a reducing property that retains the NO in bioactive form.