The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9445992 B1

PDF
Full Text
Expired
Date of Patent:
Sep. 20, 2016

Filed:

Nov. 25, 2010
Applicants:

Paolo Botti, Vessy/Geneva, CH;

Sylvie Tchertchian, Monnetier-Mornex, FR;

Inventors:

Paolo Botti, Vessy/Geneva, CH;

Sylvie Tchertchian, Monnetier-Mornex, FR;

Assignee:

ARISGEN SA, , CH;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/02 (2006.01); C07K 2/00 (2006.01); A61K 38/22 (2006.01); A61K 9/00 (2006.01); A61K 9/12 (2006.01); A61K 38/26 (2006.01); A61K 47/22 (2006.01); A61K 47/48 (2006.01);
U.S. Cl.
CPC ...
A61K 9/006 (2013.01); A61K 9/12 (2013.01); A61K 38/02 (2013.01); A61K 38/26 (2013.01); A61K 47/22 (2013.01); A61K 47/48061 (2013.01);
Abstract

Compositions and methods are provided for mucosal delivery of peptides. The compositions include a stably hydrated peptide active agent complexed with a crown compound and/or a counter ion solubilized in a non-aqueous hydrophobic vehicle at a pH different from the pI of the peptide active agent. The methods include administering to a subject an effective amount of a composition of the disclosure. Other aspects include methods for the manufacture of the compositions of the disclosure. Also provided are compositions and kits that find use in practicing embodiments of the disclosure. The methods and compositions find use in a variety of applications, including the treatment of a variety of different disease conditions.


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