The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 20, 2016

Filed:

Jun. 17, 2011
Applicants:

Chao Han, Beijing, CN;

Guoliang Huang, Beijing, CN;

Jing Cheng, Beijing, CN;

Inventors:

Chao Han, Beijing, CN;

Guoliang Huang, Beijing, CN;

Jing Cheng, Beijing, CN;

Assignees:

Tsinghua University, Beijing, CN;

CapitalBio Corporation, Beijing, CN;

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61B 17/43 (2006.01); A61B 17/435 (2006.01); B01L 3/00 (2006.01); C12M 3/00 (2006.01); C12M 3/06 (2006.01); C12M 1/00 (2006.01);
U.S. Cl.
CPC ...
A61B 17/43 (2013.01); A61B 17/435 (2013.01); B01L 3/502761 (2013.01); B01L 2200/0652 (2013.01); B01L 2200/0689 (2013.01); B01L 2300/0851 (2013.01); B01L 2400/086 (2013.01); C12M 21/06 (2013.01); C12M 23/16 (2013.01); C12M 47/04 (2013.01);
Abstract

An integrated microfluidic device and its usage are provided. The microfluidic device comprises an upper layer () and a lower layer (), wherein the lower layer () is bound to the upper layer (). The upper layer () comprises a micro-channel () and the lower layer () comprises a micro-well () array. The micro-channel () is in fluidic connection with the micro-well () array, and the height of the micro-channel () is greater than the diameter of the oocyte () flowing through the micro-channel (). The integrated microfluidic device has many advantages including low cost, high integration, and convenient operation, and has application prospects in reproductive medicine and the research of fertilization and embryo early development.


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