The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 20, 2016
Filed:
May. 29, 2012
Francisco Lozano Soto, Barcelona, ES;
Vanessa Gabriela Martinez, Barcelona, ES;
Rafael Fenutria Aumesquet, Barcelona, ES;
Francisco Lozano Soto, Barcelona, ES;
Vanessa Gabriela Martinez, Barcelona, ES;
Rafael Fenutria Aumesquet, Barcelona, ES;
FUNDACIO CLINIC PER A LA RECERCA BIOMEDICA, Barcelona, ES;
HOSPITAL CLINIC I PROVINCIAL DE BARCELONA, Barcelona, ES;
UNIVERSITAT DE BARCELONA, Barcelona, ES;
Abstract
The present invention discloses soluble isoforms of CD5 and CD6, which are scavenger-like lymphocyte receptors, for use in the prophylaxis or therapy of disorders or in therapeutic interventions, which would benefit from an exacerbated immune response to either endogenous or exogenous antigens, resulting from a decrease in lymphocyte subpopulations with regulatory functions and/or increase in lymphocyte subpopulations with effector functions. Special disorders are cell growth disorders, and chronic infections of bacterial, viral, fungal or parasitic origin. The invention also provides animal models for the study and the prophylaxis/treatment of autoimmune diseases, cancer, and chronic infections.