The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 13, 2016

Filed:

Jul. 09, 2013
Applicant:

Biocare Medical, Llc, Concord, CA (US);

Inventors:

Stephen Barker, Concord, CA (US);

Saradha Avantsa, Concord, CA (US);

Assignee:

Biocare Medical, LLC, Concord, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 1/30 (2006.01); G01N 1/31 (2006.01); G01N 33/543 (2006.01); G01N 33/58 (2006.01); B01F 11/00 (2006.01); B01F 13/00 (2006.01); G01N 35/00 (2006.01);
U.S. Cl.
CPC ...
G01N 1/31 (2013.01); B01F 11/0071 (2013.01); B01F 13/0083 (2013.01); G01N 1/312 (2013.01); G01N 33/54346 (2013.01); G01N 33/587 (2013.01); G01N 35/0098 (2013.01); Y10T 436/25 (2015.01);
Abstract

Systems and methods of sample and staining processing including compression and dynamic movement of liquids in a fluidically moving substantially contained liquid bridge perhaps between a hydrophobic wand and a hydrophilic sample support element. Embodiments may include low volume reagent and perhaps even low volume buffer wash in sample processing. In addition, antibodies can be conjugated with nanoparticles and can be used in sample processing. Exposing a sample with or without movement to AC, DC, or even a permanent magnet field may improve staining. Staining with nanoparticle reagents could be quantified using a microscope with a magnetometer below the slide viewing area. The detection of nanoparticles attached to the chemistry may facilitate the quantification of cancerous cells stained in the tissue.


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