The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 13, 2016
Filed:
Jan. 06, 2014
Applicant:
Deutsches Krebsforschungszentrum, Heidelberg, DE;
Inventors:
Nazim El-Andaloussi, Heidelberg, DE;
Antonio Marchini, Heidelberg, DE;
Jean Rommelaere, Heidelberg, DE;
Assignee:
DEUTSCHES KREBSFORSCHUNGSZENTRUM, Heidelberg, DE;
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 7/00 (2006.01); C12N 15/86 (2006.01);
U.S. Cl.
CPC ...
C12N 15/86 (2013.01); C12N 7/00 (2013.01); C12N 2710/10331 (2013.01); C12N 2710/10344 (2013.01); C12N 2750/14332 (2013.01); C12N 2750/14351 (2013.01); C12N 2799/02 (2013.01); C12N 2830/006 (2013.01);
Abstract
Described is a chimerical adenovirus-parvovirus vector characterized in that it comprises the entire parvovirus genome inserted into a adenovirus genome, wherein: (a) the adenovirus genome is characterized by deletion of E1 and E3, and (b) the biological activity of the parvoviral protein NS, preferably NS1, is reduced or eliminated.