The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 13, 2016

Filed:

Mar. 01, 2006
Applicants:

Peter Michael Waterhouse, Canberra, AU;

Ming-bo Wang, Kaleen, AU;

Michael Wayne Graham, Jindalee, AU;

Inventors:

Peter Michael Waterhouse, Canberra, AU;

Ming-Bo Wang, Kaleen, AU;

Michael Wayne Graham, Jindalee, AU;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/11 (2006.01); C12N 15/82 (2006.01); A61K 48/00 (2006.01);
U.S. Cl.
CPC ...
C12N 15/8283 (2013.01); C12N 15/8218 (2013.01); C12N 15/8247 (2013.01); C12N 15/8282 (2013.01); A01K 2217/05 (2013.01); A61K 48/00 (2013.01);
Abstract

Methods and means are provided for reducing the phenotypic expression of a nucleic acid of interest in eucaryotic cells, particularly in plant cells, by introducing chimeric genes encoding sense and antisense RNA molecules directed towards the target nucleic acid, which are capable of forming a double stranded RNA region by base-pairing between the regions with sense and antisense nucleotide sequence or by introducing the RNA molecules themselves. Preferably, the RNA molecules comprises simultaneously both sense and antisense nucleotide sequence.


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