The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 13, 2016
Filed:
Jul. 18, 2013
Applicant:
Academisch Ziekenhuis Leiden H.o.d.n. Lumc, Leiden, NL;
Inventors:
Jan Kessler, Leiden, NL;
Marieke Griffioen, Alphen a/d Rijn, NL;
Cornelis Johannes Maria Melief, Haarlem, NL;
Jan Wouter Drijfhout, Leiden, NL;
Assignee:
Academisch Ziekenhuis Leiden H.O.D.N. LUMC, Leiden, NL;
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01); C07K 14/47 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/4748 (2013.01); A61K 39/0011 (2013.01); A61K 39/00 (2013.01); A61K 2039/57 (2013.01); A61K 2039/572 (2013.01);
Abstract
The invention relates to a peptide having a length of no more than 100 amino acids and comprising at least 19 contiguous amino acids from the amino acid sequence of the human PRAME protein, wherein the peptide comprises at least one HLA class II epitope and at least one HLA class I epitope from the amino acid sequence of the human PRAME protein and to its use as such or in a composition as a medicament for the treatment and/or prevention of cancer.