The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 13, 2016
Filed:
Mar. 22, 2012
Hak Sung Kim, Daejeon, KR;
Dong Sup Kim, Daejeon, KR;
Sang Chul Lee, Daejeon, KR;
Byung Chul Lee, Seoul, KR;
Ji Eun Han, Daejeon, KR;
Joong Jae Lee, Daejeon, KR;
Keun Wan Park, Daejeon, KR;
Seung Pyo Hong, Daejeon, KR;
Hak Sung Kim, Daejeon, KR;
Dong Sup Kim, Daejeon, KR;
Sang Chul Lee, Daejeon, KR;
Byung Chul Lee, Seoul, KR;
Ji Eun Han, Daejeon, KR;
Joong Jae Lee, Daejeon, KR;
Keun Wan Park, Daejeon, KR;
Seung Pyo Hong, Daejeon, KR;
KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY, Daejeon, KR;
Abstract
The present invention relates to a soluble polypeptide comprised of repeat modules. More particularly, the present invention relates to a soluble fusion polypeptide of the N-terminal domain of internalin and LRR (Leucine rich repeat) family protein, a method for preparing the polypeptide, a vector comprising a nucleic acid sequence encoding the polypeptide, a host cell comprising the vector, a method for producing a solubility and folding-improved fusion polypeptide by expressing the vector in the host cell, and a method for improving the solubility and folding of the fusion polypeptide. Further, the present invention relates to a method for preparing the polypeptide bound with a specific target and analyzing the efficacy of the soluble polypeptide.