The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 13, 2016
Filed:
Jun. 18, 2015
Genentech, Inc., South San Francisco, CA (US);
Hazel Joan Dyke, Harlow, GB;
Lewis Gazzard, South San Francisco, CA (US);
Karen Williams, Harlow, GB;
Huifen Chen, South San Francisco, CA (US);
Samuel Kintz, South San Francisco, CA (US);
Joy Drobnick, South San Francisco, CA (US);
Joseph P. Lyssikatos, South San Francisco, CA (US);
Simon Goodacre, Harlow, GB;
Calum Macleod, Harlow, GB;
Charles Ellwood, Harlow, GB;
GENENTECH, INC., South San Francisco, CA (US);
Abstract
The invention relates to 1,7-diazacarbazole compounds of Formula (I), (I-a) and (I-b) which are useful as kinase inhibitors, more specifically useful as checkpoint kinase 1 (chk1) inhibitors, thus useful as cancer therapeutics. The invention also relates to compositions, more specifically pharmaceutical compositions comprising these compounds and methods of using the same to treat various forms of cancer and hyperproliferative disorders, as well as methods of using the compounds for in vitro, in situ, and in vivo diagnosis or treatment of mammalian cells, or associated pathological conditions.