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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9440922 B1

PDFFull Text
Date of Patent:
Sep. 13, 2016

Filed:

Feb. 11, 2015

Tetracyclic compound

Applicant:

Chugai Seiyaku Kabushiki Kaisha, Kita-ku, Tokyo, JP;

Inventors:

Kazutomo Kinoshita, Kanagawa, JP;

Kohsuke Asoh, Kanagawa, JP;

Noriyuki Furuichi, Kanagawa, JP;

Toshiya Ito, Kanagawa, JP;

Hatsuo Kawada, Kanagawa, JP;

Nobuya Ishii, Kanagawa, JP;

Hiroshi Sakamoto, Kanagawa, JP;

WooSang Hong, Gyeonggi-do, KR;

MinJeong Park, Gyeonggi-do, KR;

Yoshiyuki Ono, Shizuoka, JP;

Yasuharu Kato, Shizuoka, JP;

Kenji Morikami, Shizuoka, JP;

Takashi Emura, Shizuoka, JP;

Nobuhiro Oikawa, Kanagawa, JP;

Assignee:

Chugai Seiyaku Kabushiki Kaisha, Tokyo, JP;

Attorney:

Foley & Lardner LLP

Primary Examiner:

Alexander R Pagano

Int. Cl.
CPC ...
A61K 31/506 (2006.01); C07D 209/56 (2006.01); C07D 209/88 (2006.01); C07D 307/77 (2006.01); C07D 307/92 (2006.01); C07D 333/50 (2006.01); C07D 333/76 (2006.01); C07D 401/04 (2006.01); C07D 401/06 (2006.01); C07D 403/04 (2006.01); C07D 405/12 (2006.01); C07D 405/14 (2006.01); C07D 471/04 (2006.01); C07D 491/107 (2006.01); A61K 31/404 (2006.01); A61K 31/4178 (2006.01); A61K 31/4439 (2006.01); A61K 31/454 (2006.01); A61K 31/496 (2006.01); A61K 31/5377 (2006.01); A61K 31/541 (2006.01); A61K 31/7056 (2006.01);
U.S. Cl.
CPC ...
C07D 209/56 (2013.01); A61K 31/404 (2013.01); A61K 31/4178 (2013.01); A61K 31/4439 (2013.01); A61K 31/454 (2013.01); A61K 31/496 (2013.01); A61K 31/506 (2013.01); A61K 31/5377 (2013.01); A61K 31/541 (2013.01); A61K 31/7056 (2013.01); C07D 209/88 (2013.01); C07D 307/77 (2013.01); C07D 307/92 (2013.01); C07D 333/50 (2013.01); C07D 333/76 (2013.01); C07D 401/04 (2013.01); C07D 401/06 (2013.01); C07D 403/04 (2013.01); C07D 405/12 (2013.01); C07D 405/14 (2013.01); C07D 471/04 (2013.01); C07D 491/107 (2013.01);
Abstract

A compound represented by the general Formula (I) below, or a salt or solvate thereof, which is useful as an ALK inhibitor, and is useful for prophylaxis or treatment of a disease accompanied by abnormality in ALK, for example, cancer, cancer metastasis, depression or cognitive function disorder:

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