The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 13, 2016
Filed:
Jul. 02, 2015
Applicant:
Wisconsin Alumni Research Foundation, Madison, WI (US);
Inventors:
Douglas Benjamin Weibel, Madison, WI (US);
Katherine Ann Hurley, Madison, WI (US);
Katherine Cassidy Faulkner, Boxborough, MA (US);
Assignee:
Wisconsin Alumni Research Foundation, Madison, WI (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 209/16 (2006.01); A61K 31/4045 (2006.01); A61K 31/137 (2006.01); A01N 43/38 (2006.01); A01N 33/10 (2006.01);
U.S. Cl.
CPC ...
C07D 209/16 (2013.01); A01N 33/10 (2013.01); A01N 43/38 (2013.01); A61K 31/137 (2013.01); A61K 31/4045 (2013.01);
Abstract
Described herein are antimicrobial compounds identified via a high-throughput screen to identify compounds that produce anucleate cells inafter cell division occurs. Compound 1 (5-nonyloxytryptamine) and its analogs are small molecule inhibitors of the nucleoid occlusion system and/or proteins that are responsible for maintaining the structure of the chromosome. The antimicrobial compounds are useful to treat bacterial infections as well as to inhibit bacterial growth.