The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 13, 2016
Filed:
Feb. 17, 2014
Applicant:
Leo Laboratories Limited, Dublin, IE;
Inventor:
Steven Martin Ogbourne, Pinbarren, AU;
Assignee:
LEO Laboratories Limited, Dublin, IE;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C 67/52 (2006.01); C07C 69/533 (2006.01); A61K 9/00 (2006.01); A61K 9/06 (2006.01);
U.S. Cl.
CPC ...
C07C 67/52 (2013.01); C07C 69/533 (2013.01); A61K 9/0014 (2013.01); A61K 9/0034 (2013.01); A61K 9/06 (2013.01); C07B 2200/13 (2013.01); C07C 2103/86 (2013.01);
Abstract
The present invention relates to a novel crystalline form of ingenol mebutate, methods of preparation thereof, and to its use. More specifically, the invention relates to the conversion of amorphous ingenol mebutate (ingenol-3-angelate, PEP005) to a crystalline form, which was characterized by single crystal X-Ray crystallography (XRC), attenuated total reflectance Fourier transform infrared (FTIR-ATR) spectroscopy and Differential Scanning calorimetry (DSC).