The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 13, 2016
Filed:
Jul. 28, 2014
Polytherics Limited, London, GB;
Stephen James Brocchini, Welwyn Garden City, GB;
Antony Robert Godwin, London, GB;
Elisa Pedone, London, GB;
Ji-Won Choi, London, GB;
Sunil Shaunak, Hertford, GB;
POLYTHERICS LIMITED, London, GB;
Abstract
Novel biologically active compounds of the general formula (I) in which one of X and X' represents a polymer, and the other represents a hydrogen atom; each Q independently represents a linking group; W represents an electron-withdrawing moiety or a moiety preparable by reduction of an electron-withdrawing moiety; or, if X′ represents a polymer, X-Q-W— together may represent an electron withdrawing group; and in addition, if X represents a polymer, X′ and electron withdrawing group W together with the interjacent atoms may form a ring; each of Zand Zindependently represents a group derived from a biological molecule, each of which is linked to A and B via an amine group; or Zand Ztogether represent a single group derived from a biological molecule which is linked to A and B via two amine groups; A is a Calkylene or alkenylene chain; and B is a bond or a Calkylene or alkenylene chain; are formed by conjugating a suitable polymer to a suitable biologically active molecule via amine groups in said molecule, preferably via a disulphide bridge.