The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 13, 2016
Filed:
Jan. 04, 2016
Massachusetts Institute of Technology, Cambridge, MA (US);
Daniel Griffith Anderson, Framingham, MA (US);
Kathryn Ann Whitehead, Pittsburgh, PA (US);
Joseph R. Dorkin, Somerville, MA (US);
Arturo Jose Vegas, Belmont, MA (US);
Yunlong Zhang, Cambridge, MA (US);
Robert S. Langer, Newton, MA (US);
Massachusetts Institute of Technology, Cambridge, MA (US);
Abstract
Provided herein are lipidoids that may be prepared from the conjugate addition of alkylamines to acrylates. In some embodiments, provided lipidoids are biodegradable and may be used in a variety of drug delivery systems. Given the amino moiety of the lipidoids, they are well-suited for the delivery of polynucleotides, in addition to other agents. Nanoparticles containing the inventive lipidoids and polynucleotides have been prepared and have been shown to be effective in delivering siRNA.